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Alpha-KetoGluterate

The salts of alpha-ketogluterate (calcium, magnesium, and potassium) have
been demonstrated to increase muscle-glutamine stores in severely catabolic
hospital patients to a greater degree than leucine. Alpha-Ketogluterate is utilized in
the Krebs cycle and provides the carbon skeleton for a portion of glutamine
synthesis. The combination of leucine and salts of alpha-ketoglutarate can provide
invaluable support for both muscle metabolism and immune functions during the
periods of stress.
The combination of KIC, leucine and salts of alpha-ketogluterate can produce
measurable anabolic effects. The strong anticatabolic effects produced by the
combination of KIC, alpha-ketogluterate and leucine can limit the uses of amino
acids for energy and promote the use of fatty acids, resulting in decreased
urine-urea nitrogen.
It is reasonable to assume that this combination of nutrients could eventually
lead to increased lean mass and decreased body fat, provided that appropriate diet
and training procedures are followed.
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